Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer with very limited therapeutic options. Cancer stem cells (CSCs) are essential for propagation of PDAC, but also for its metastatic activity and chemoresistance. To date, it is still unclear how cancer stem cells (C...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Walter, Karolin, Rodriguez-Aznar, Eva, Ferreira, Monica S. Ventura, Frappart, Pierre-Olivier, Dittrich, Tabea, Tiwary, Kanishka, Meessen, Sabine, Lerma, Laura, Daiss, Nora, Schulte, Lucas-Alexander, Najafova, Zeynab, Arnold, Frank, Usachov, Valentyn, Azoitei, Ninel, Erkan, Mert, Lechel, Andre, Brümmendorf, Tim H., Seufferlein, Thomas, Kleger, Alexander, Tabarés, Enrique, Günes, Cagatay, Johnsen, Steven A., Beier, Fabian, Sainz, Bruno, Hermann, Patrick C.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268125/
https://ncbi.nlm.nih.gov/pubmed/34201898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133145
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