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Identification of the Target for a Transition Metal-α-Amino Acid Complex Antibiotic Against Mycobacterium smegmatis
Spontaneous mutants of Mycobacterium smegmatis strain mc(2)155 resistant to 1-PG (iridium-L-phenylglycine complex), an antimycobacterial antibiotic, were isolated. Based on the discovery that some 1-PG-resistant mutants (1-PG (R)) were also resistant to high concentrations of clarithromycin (≥250 μg...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8268012/ https://ncbi.nlm.nih.gov/pubmed/34248636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.686358 |
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