Hepatic Branch Vagotomy Modulates the Gut-Liver-Brain Axis in Murine Cirrhosis

BACKGROUND: Cirrhosis and hepatic encephalopathy (HE) are linked with an altered gut-liver-brain axis, however, the relative contribution of hepatic vagal innervation is unclear. We aimed to determine the impact of hepatic vagotomy on the gut microbiome, brain, and liver in murine cirrhosis. METHODS...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zhang, Yuan, Kang, Jason D., Zhao, Derrick, Ghosh, Siddartha S., Wang, Yanyan, Tai, Yunling, Gonzalez-Maeso, Javier, Sikaroodi, Masoumeh, Gillevet, Patrick M., Lippman, H. Robert, Hylemon, Phillip B., Zhou, Huiping, Bajaj, Jasmohan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268007/
https://ncbi.nlm.nih.gov/pubmed/34248683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.702646
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