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Zn-Enhanced Asp-Rich Antimicrobial Peptides: N-Terminal Coordination by Zn(II) and Cu(II), Which Distinguishes Cu(II) Binding to Different Peptides

The antimicrobial activity of surfactant-associated anionic peptides (SAAPs), which are isolated from the ovine pulmonary surfactant and are selective against the ovine pathogen Mannheimia haemolytica, is strongly enhanced in the presence of Zn(II) ions. Both calorimetry and ITC measurements show th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Miller, Adriana, Matera-Witkiewicz, Agnieszka, Mikołajczyk, Aleksandra, Wątły, Joanna, Wilcox, Dean, Witkowska, Danuta, Rowińska-Żyrek, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267837/
https://ncbi.nlm.nih.gov/pubmed/34203496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136971
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