Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers

BACKGROUND: Vaccination with radiation-attenuated Plasmodium falciparum sporozoites is known to induce protective immunity. However, the mechanisms underlying this protection remain unclear. In this work, two recent radiation-attenuated sporozoite vaccination studies were used to identify potential...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Duffy, Fergal J., Du, Ying, Carnes, Jason, Epstein, Judith E., Hoffman, Stephen L., Abdulla, Salim, Jongo, Said, Mpina, Maxmillian, Daubenberger, Claudia, Aitchison, John D., Stuart, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267772/
https://ncbi.nlm.nih.gov/pubmed/34243763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03839-3
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