Complement Inhibition for Geographic Atrophy: A Tempting Target with Mixed Results

Age-related macular degeneration (AMD) is a leading cause of blindness in older adults. One of the strongest genetic risk factors for AMD is a complement factor H (CFH) gene polymorphism characterized by a tyrosine-histidine change at amino acid position 402 (Y402H). The magnitude of this associatio...

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Udgivet i:J Clin Med
Main Authors: Lin, Jonathan B., Halawa, Omar A., Miller, Joan W., Vavvas, Demetrios G.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Opinion
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267692/
https://ncbi.nlm.nih.gov/pubmed/34209660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10132890
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