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Upregulated Chemokine and Rho-GTPase Genes Define Immune Cell Emigration into Salivary Glands of Sjögren’s Syndrome-Susceptible C57BL/6.NOD-Aec1Aec2 Mice

The C57BL/6.NOD-Aec1Aec2 mouse is considered a highly appropriate model of Sjögren’s Syndrome (SS), a human systemic autoimmune disease characterized primarily as the loss of lacrimal and salivary gland functions. This mouse model, as well as other mouse models of SS, have shown that B lymphocytes a...

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Pubblicato in:Int J Mol Sci
Autori principali: Peck, Ammon B., Nguyen, Cuong Q., Ambrus, Julian L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267620/
https://ncbi.nlm.nih.gov/pubmed/34281229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137176
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