Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma

Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent results. Mice bearing F420 showed no response, whereas thos...

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Udgivet i:iScience
Main Authors: Wedekind, Mary Frances, Miller, Katherine E., Chen, Chun-Yu, Wang, Pin-Yi, Hutzen, Brian J., Currier, Mark A., Nartker, Brooke, Roberts, Ryan D., Boon, Louis, Conner, Joe, LaHaye, Stephanie, Kelly, Benjamin J., Gordon, David, White, Peter, Mardis, Elaine R., Cripe, Timothy P.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
https://ncbi.nlm.nih.gov/pubmed/34278266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102759
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