Prostaglandin F2α protects against pericyte apoptosis by inhibiting the PI3K/Akt/GSK3β/β-catenin signaling pathway

BACKGROUND: Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and the main cause of non-traumatic blindness in adults. Pericyte loss is known to be an early pathological change of DR. Our group’s previous research indicated that prostaglandin F2α (PGF2α) acts as an...

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Publicat a:Ann Transl Med
Autors principals: Cheng, Ying, Peng, Liyuan, Deng, Xiaoqing, Li, Ting, Guo, Hang, Xu, Chaofei, Fang, Ting, Liu, Xiaohuan, Sun, Bei, Chen, Liming
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267281/
https://ncbi.nlm.nih.gov/pubmed/34277821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-21-2717
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