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Chronic Naltrexone Therapy Is Associated with Improved Cardiac Function in Volume Overloaded Rats

PURPOSE: Myocardial opioid receptors were demonstrated in animals and humans and seem to colocalize with membranous and sarcolemmal calcium channels of the excitation–contraction coupling in the left ventricle (LV). Therefore, this study investigated whether blockade of the cardiac opioid system by...

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Detalhes bibliográficos
Publicado no:Cardiovasc Drugs Ther
Main Authors: Dehe, Lukas, Shaqura, Mohammed, Nordine, Michael, Habazettl, Helmut, von Kwiatkowski, Petra, Schluchter, Helena, Shakibaei, Mehdi, Mousa, Shaaban A., Schäfer, Michael, Treskatsch, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266787/
https://ncbi.nlm.nih.gov/pubmed/33484395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-020-07132-4
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