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Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA
The rnlAB toxin-antitoxin operon from Escherichia coli functions as an anti-phage defense system. RnlA was identified as a member of the HEPN (Higher Eukaryotes and Prokaryotes Nucleotide-binding domain) superfamily of ribonucleases. The activity of the toxin RnlA requires tight regulation by the an...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8266594/ https://ncbi.nlm.nih.gov/pubmed/34139012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab513 |
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