Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication

Mosquito-borne flaviviruses (MBFVs) including dengue, West Nile, yellow fever, and Zika viruses have an RNA genome encoding one open reading frame flanked by 5′ and 3′ untranslated regions (UTRs). The 3′ UTRs of MBFVs contain regions of high sequence conservation in structured RNA elements known as...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Akiyama, Benjamin M, Graham, Monica E, O′Donoghue, Zoe, Beckham, J David, Kieft, Jeffrey S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266583/
https://ncbi.nlm.nih.gov/pubmed/34133732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab462
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