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BET family members Bdf1/2 modulate global transcription initiation and elongation in Saccharomyces cerevisiae

Human bromodomain and extra-terminal domain (BET) family members are promising targets for therapy of cancer and immunoinflammatory diseases, but their mechanisms of action and functional redundancies are poorly understood. Bdf1/2, yeast homologues of the human BET factors, were previously proposed...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Donczew, Rafal, Hahn, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266393/
https://ncbi.nlm.nih.gov/pubmed/34137374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.69619
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