Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy

Homozygous deletion (HD) of the tumor suppressor gene CDKN2A is the most frequent genetic alteration in malignant pleural mesothelioma and is also frequent in non-small cell lung cancers. This HD is often accompanied by the HD of the type I interferons (IFN I) genes that are located closed to the CD...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Grard, Marion, Chatelain, Camille, Delaunay, Tiphaine, Pons-Tostivint, Elvire, Bennouna, Jaafar, Fonteneau, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266377/
https://ncbi.nlm.nih.gov/pubmed/34249754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.695770
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