Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

Background: Subarachnoid hemorrhage (SAH) is a life-threatening disease worldwide, and effective pharmaceutical treatment is still lacking. Celastrol is a plant-derived triterpene which showed neuroprotective potential in several types of brain insults. This study aimed to investigate the effects of...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Xu, Hangzhe, Cai, Yong, Yu, Mengyan, Sun, Jing, Cai, Jing, Li, Jingbo, Qin, Bing, Ying, Guangyu, Chen, Ting, Shen, Yongfeng, Jie, Liyong, Xu, Demin, Gu, Chi, Wang, Chun, Hu, XiaoYi, Chen, Jingsen, Wang, Lin, Chen, Gao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2021
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266331/
https://ncbi.nlm.nih.gov/pubmed/34182541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203221
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