Ratiometric Detection of Glutathione Based on Disulfide Linkage Rupture between a FRET Coumarin Donor and a Rhodamine Acceptor

Abnormal levels of glutathione, a cellular antioxidant, can lead to a variety of diseases. We have constructed a near-infrared ratiometric fluorescent probe to detect glutathione concentrations in biological samples. The probe consists of a coumarin donor, which is connected through a disulfide-teth...

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Pubblicato in:Chembiochem
Autori principali: Zhang, Yibin, Xia, Shuai, Wan, Shulin, Steenwinkel, Tessa E., Vohs, Tara, Luck, Rudy L., Werner, Thomas, Liu, Haiying
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265326/
https://ncbi.nlm.nih.gov/pubmed/33983667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202100108
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