Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathways

BACKGROUND: Leptin plays a critical role in the regulation of metabolic homeostasis. However, the molecular mechanism and cross talks between leptin and metabolic pathways leading to metabolic homeostasis across different species are not clear. This study aims to explore the effects of leptin in mic...

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Bibliografski detalji
Izdano u:Cell Biosci
Glavni autori: Ding, Yi, Haks, Mariëlle C., Forn-Cuní, Gabriel, He, Junling, Nowik, Natalia, Harms, Amy C., Hankemeier, Thomas, Eeza, Muhamed N. H., Matysik, Jörg, Alia, A., Spaink, Herman P.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265131/
https://ncbi.nlm.nih.gov/pubmed/34233759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00642-0
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