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Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metabolite Profiles of Its Hydroxylated Metabolites

[Image: see text] The characterization of the metabolism of lower chlorinated PCB, such as 4-chlorobiphenyl (PCB3), is challenging because of the complex metabolite mixtures formed in vitro and in vivo. We performed parallel metabolism studies with PCB3 and its hydroxylated metabolites to characteri...

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Publié dans:Environ Sci Technol
Auteurs principaux: Zhang, Chun-Yun, Flor, Susanne, Ruiz, Patricia, Ludewig, Gabriele, Lehmler, Hans-Joachim
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264946/
https://ncbi.nlm.nih.gov/pubmed/34125531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.1c01076
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