Leptin and Melanocortin Signaling Mediates Hypertension in Offspring From Female Rabbits Fed a High-Fat Diet During Gestation and Lactation

Maternal high-fat diet in rabbits leads to hypertension and elevated renal sympathetic nerve activity (RSNA) in adult offspring but whether this is due to adiposity or maternal programming is unclear. We gave intracerebroventricular (ICV) and ventromedial hypothalamus (VMH) administration of leptin-...

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Bibliografski detalji
Izdano u:Front Physiol
Glavni autori: Lim, Kyungjoon, Burke, Sandra L., Marques, Francine Z., Jackson, Kristy L., Gueguen, Cindy, Sata, Yusuke, Armitage, James A., Head, Geoffrey A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Physiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264761/
https://ncbi.nlm.nih.gov/pubmed/34248679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.693157
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