Leptin and Melanocortin Signaling Mediates Hypertension in Offspring From Female Rabbits Fed a High-Fat Diet During Gestation and Lactation

Maternal high-fat diet in rabbits leads to hypertension and elevated renal sympathetic nerve activity (RSNA) in adult offspring but whether this is due to adiposity or maternal programming is unclear. We gave intracerebroventricular (ICV) and ventromedial hypothalamus (VMH) administration of leptin-...

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Bibliografiska uppgifter
I publikationen:Front Physiol
Huvudupphovsmän: Lim, Kyungjoon, Burke, Sandra L., Marques, Francine Z., Jackson, Kristy L., Gueguen, Cindy, Sata, Yusuke, Armitage, James A., Head, Geoffrey A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Physiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264761/
https://ncbi.nlm.nih.gov/pubmed/34248679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.693157
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