Identification of Koumine as a Translocator Protein 18 kDa Positive Allosteric Modulator for the Treatment of Inflammatory and Neuropathic Pain

Koumine is an alkaloid that displays notable activity against inflammatory and neuropathic pain, but its therapeutic target and molecular mechanism still need further study. Translocator protein 18 kDa (TSPO) is a vital therapeutic target for pain treatment, and recent research implies that there ma...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xiong, Bojun, Jin, Guilin, Xu, Ying, You, Wenbing, Luo, Yufei, Fang, Menghan, Chen, Bing, Huang, Huihui, Yang, Jian, Lin, Xu, Yu, Changxi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264504/
https://ncbi.nlm.nih.gov/pubmed/34248642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.692917
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