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Exploring the Genotype–Phenotype Correlation in GBA-Parkinson Disease: Clinical Aspects, Biomarkers, and Potential Modifiers

Variants in the glucocerebrosidase (GBA) gene are the most common genetic risk factor for Parkinson disease (PD). These include pathogenic variants causing Gaucher disease (GD) (divided into “severe,” “mild,” or “complex”—resulting from recombinant alleles—based on the phenotypic effects in GD) and...

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Bibliografiske detaljer
Udgivet i:Front Neurol
Main Authors: Menozzi, Elisa, Schapira, Anthony H. V.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264189/
https://ncbi.nlm.nih.gov/pubmed/34248830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.694764
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