Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast‐derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation

Extracellular vesicles (EVs) are emerging in tissue engineering as promising acellular tools, circumventing many of the limitations associated with cell‐based therapies. Epigenetic regulation through histone deacetylase (HDAC) inhibition has been shown to increase differentiation capacity. Therefore...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Man, Kenny, Brunet, Mathieu Y., Fernandez‐Rhodes, Maria, Williams, Soraya, Heaney, Liam M., Gethings, Lee A., Federici, Angelica, Davies, Owen G., Hoey, David, Cox, Sophie C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263905/
https://ncbi.nlm.nih.gov/pubmed/34262674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12118
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