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Calmodulin-dependent KCNE4 dimerization controls membrane targeting

The voltage-dependent potassium channel Kv1.3 participates in the immune response. Kv1.3 is essential in different cellular functions, such as proliferation, activation and apoptosis. Because aberrant expression of Kv1.3 is linked to autoimmune diseases, fine-tuning its function is crucial for leuko...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Roig, Sara R., Solé, Laura, Cassinelli, Silvia, Colomer-Molera, Magalí, Sastre, Daniel, Serrano-Novillo, Clara, Serrano-Albarrás, Antonio, Lillo, M. Pilar, Tamkun, Michael M., Felipe, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263776/
https://ncbi.nlm.nih.gov/pubmed/34234241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93562-5
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