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Drying and temperature induced conformational changes of nucleic acids and stallion sperm chromatin in trehalose preservation formulations

Even though dried sperm is not viable, it can be used for fertilization as long as its chromatin remains intact. In this study, we investigated drying- and temperature-induced conformational changes of nucleic acids and stallion sperm chromatin. Sperm was diluted in preservation formulations with an...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Brogna, Raffaele, Fan, Juezhu, Sieme, Harald, Wolkers, Willem F., Oldenhof, Harriëtte
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263733/
https://ncbi.nlm.nih.gov/pubmed/34234244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93569-y
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