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A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway

Gastric cancer (GC) is one of the most common malignant tumors worldwide and has high rates of morbidity and mortality. This study investigated the role of Krüppel-like factor 16 (KLF16) in GC. Real-time polymerase chain reaction, Western blotting, and immunohistochemistry were used to examine the e...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Sun, Ding-Ping, Tian, Yu-Feng, Lin, Chih-Chan, Hung, Shih-Ting, Uen, Yih-Huei, Hseu, You-Cheng, Chou, Chia-Lin, Cheng, Li-Chin, Wang, Wen-Ching, Kuang, Yi-Yu, Fang, Chia-Lang, Lin, Kai-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263687/
https://ncbi.nlm.nih.gov/pubmed/34249424
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