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Genotype imputation in case-only studies of gene-environment interaction: validity and power
Case-only (CO) studies are a powerful means to uncover gene-environment (G × E) interactions for complex human diseases. Moreover, such studies may in principle also draw upon genotype imputation to increase statistical power even further. However, genotype imputation usually employs healthy control...
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| Udgivet i: | Hum Genet |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8263402/ https://ncbi.nlm.nih.gov/pubmed/34041609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-021-02294-z |
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