OMIC-05. PHOSPHOPROTEOMIC ANALYSIS IDENTIFIES SUBGROUP ENRICHED PATHWAYS AND KINASE SIGNATURES IN MEDULLOBLASTOMA

Medulloblastoma (MB) is classified into four molecular subgroups: wingless (WNT), sonic hedgehog (SHH), Group 3 (G3) and Group 4 (G4), each with different molecular profiles and patient outcomes. Subgroup heterogeneity and low mutational burdens have hindered the identification of actionable therape...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Leskoske, Kristin, Garcia-Mansfield, Krystine, Krishnan, Aparna, Sharma, Ritin, Rusert, Jessica, Mesirov, Jill, Wechsler-Reya, Robert, Pirrotte, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Omics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263200/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.152
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