Phase Variation in HMW1A Controls a Phenotypic Switch in Haemophilus influenzae Associated with Pathoadaptation during Persistent Infection

Genetic variants arising from within-patient evolution shed light on bacterial adaptation during chronic infection. Contingency loci generate high levels of genetic variation in bacterial genomes, enabling adaptation to the stringent selective pressures exerted by the host. A significant gap in our...

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Vydáno v:mBio
Hlavní autoři: Fernández-Calvet, Ariadna, Euba, Begoña, Gil-Campillo, Celia, Catalan-Moreno, Arancha, Moleres, Javier, Martí, Sara, Merlos, Alexandra, Langereis, Jeroen D., García-del Portillo, Francisco, Bakaletz, Lauren O., Ehrlich, Garth D., Porsch, Eric A., Menéndez, Margarita, Mell, Joshua C., Toledo-Arana, Alejandro, Garmendia, Junkal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262952/
https://ncbi.nlm.nih.gov/pubmed/34154422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00789-21
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