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Analysis of the Oxidative Stress Regulon Identifies soxS as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

In bacteria, the defense system deployed to counter oxidative stress is orchestrated by three transcriptional factors, SoxS, SoxR, and OxyR. Although the regulon that these factors control is known in many bacteria, similar data are not available for Klebsiella pneumoniae. To address this data gap,...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Anes, João, Dever, Katherine, Eshwar, Athmanya, Nguyen, Scott, Cao, Yu, Sivasankaran, Sathesh K., Sakalauskaitė, Sandra, Lehner, Angelika, Devineau, Stéphanie, Daugelavičius, Rimantas, Stephan, Roger, Fanning, Séamus, Srikumar, Shabarinath
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262902/
https://ncbi.nlm.nih.gov/pubmed/34098732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00867-21
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