The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place

Glycosomes are peroxisome-related organelles of trypanosomatid parasites containing metabolic pathways, such as glycolysis and biosynthesis of sugar nucleotides, usually present in the cytosol of other eukaryotes. UDP-glucose pyrophosphorylase (UGP), the enzyme responsible for the synthesis of the s...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Villafraz, Oriana, Baudouin, Hélène, Mazet, Muriel, Kulyk, Hanna, Dupuy, Jean-William, Pineda, Erika, Botté, Cyrille, Inaoka, Daniel Ken, Portais, Jean-Charles, Bringaud, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262884/
https://ncbi.nlm.nih.gov/pubmed/34044588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00375-21
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