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mmCSM-PPI: predicting the effects of multiple point mutations on protein–protein interactions

Protein–protein interactions play a crucial role in all cellular functions and biological processes and mutations leading to their disruption are enriched in many diseases. While a number of computational methods to assess the effects of variants on protein–protein binding affinity have been propose...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Rodrigues, Carlos H M, Pires, Douglas E V, Ascher, David B
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262703/
https://ncbi.nlm.nih.gov/pubmed/33893812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab273
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