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Current Therapeutic Strategies in BRAF-Mutant Metastatic Colorectal Cancer

Around 8–12% of patients with advanced colon rectal cancer (CRC) present with BRAF alterations, in particular V600E mutation, which is associated with right-side, poorly differentiated and mucinous type tumors. The presence of BRAF mutation (BRAF-mt) has been identified as a hallmark of poor prognos...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Grassi, Elisa, Corbelli, Jody, Papiani, Giorgio, Barbera, Maria Aurelia, Gazzaneo, Federica, Tamberi, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262685/
https://ncbi.nlm.nih.gov/pubmed/34249672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.601722
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