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Role and mechanism of chaperones calreticulin and ERP57 in restoring trafficking to mutant HERG-A561V protein

Long QT syndrome type 2 is caused by a mutation in the human-ether-a-go-go-related gene (HERG) gene encoding the rapidly activating delayed rectifier K-current. HERG is a key cell membrane glycoprotein; however, whether the maturation process of HERG protein involves key molecules derived from the c...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Med
Asıl Yazarlar: Wu, Yujia, Huang, Xiaoyan, Zheng, Zequn, Yang, Xi, Ba, Yanna, Lian, Jiangfang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262656/
https://ncbi.nlm.nih.gov/pubmed/34212985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2021.4992
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