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Molecular clock REV-ERBα regulates cigarette smoke–induced pulmonary inflammation and epithelial-mesenchymal transition

Cigarette smoke (CS) is the main etiological factor in the pathogenesis of emphysema/chronic obstructive pulmonary disease (COPD), which is associated with abnormal epithelial-mesenchymal transition (EMT). Previously, we have shown an association among circadian rhythms, CS-induced lung inflammation...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wang, Qixin, Sundar, Isaac K., Lucas, Joseph H., Muthumalage, Thivanka, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262497/
https://ncbi.nlm.nih.gov/pubmed/34014841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.145200
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