Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick–transmitted Borreliella spirochetal infection known as Lyme disease. T cells and innate immune cells have previously been shown to predominate the EM lesion and promote the reaction. Despite the established importance of B c...

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Udgivet i:JCI Insight
Main Authors: Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B., Dardick, Kenneth R., Belperron, Alexia A., Montgomery, Ruth R., Shalek, Alex K., Hafler, David A., Kleinstein, Steven H., Bockenstedt, Linda K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262471/
https://ncbi.nlm.nih.gov/pubmed/34061047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.148035
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