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Age-specific effects of vaccine egg adaptation and immune priming on A(H3N2) antibody responses following influenza vaccination

A(H3N2) influenza vaccine effectiveness (VE) was low during the 2016–19 seasons and varied by age. We analyzed neutralizing antibody responses to egg- and cell-propagated A(H3N2) vaccine and circulating viruses following vaccination in 375 individuals (aged 7 months to 82 years) across all vaccine-e...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Liu, Feng, Gross, F. Liaini, Jefferson, Stacie N., Holiday, Crystal, Bai, Yaohui, Wang, Li, Zhou, Bin, Levine, Min Z.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262463/
https://ncbi.nlm.nih.gov/pubmed/33690218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI146138
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