Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes

Abnormal action potential (AP) properties, as occurs in long or short QT syndromes (LQTS and SQTS, respectively), can cause life-threatening arrhythmias. Optogenetics strategies, utilizing light-sensitive proteins, have emerged as experimental platforms for cardiac pacing, resynchronization, and def...

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Publicat a:JCI Insight
Autors principals: Gruber, Amit, Edri, Oded, Huber, Irit, Arbel, Gil, Gepstein, Amira, Shiti, Assad, Shaheen, Naim, Chorna, Snizhana, Landesberg, Michal, Gepstein, Lior
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262308/
https://ncbi.nlm.nih.gov/pubmed/34100384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.147470
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