Loss of diacylglycerol kinase ε causes thrombotic microangiopathy by impairing endothelial VEGFA signaling

Loss of function of the lipid kinase diacylglycerol kinase ε (DGKε), encoded by the gene DGKE, causes a form of atypical hemolytic uremic syndrome that is not related to abnormalities of the alternative pathway of the complement, by mechanisms that are not understood. By generating a potentially nov...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Liu, Dingxiao, Ding, Qiong, Dai, Dao-Fu, Padhy, Biswajit, Nayak, Manasa K., Li, Can, Purvis, Madison, Jin, Heng, Shu, Chang, Chauhan, Anil K., Huang, Chou-Long, Attanasio, Massimo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262293/
https://ncbi.nlm.nih.gov/pubmed/33986189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146959
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