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Case Report: A Case Report of a Histological Transformation of ALK-Rearranged Adenocarcinoma With High Expression of PD-L1 to Squamous Cell Carcinoma After Treatment With Alectinib

We report an anaplastic lymphoma kinase (ALK)-positive patient shows a poor response to the ALK inhibitor alectinib due to the high expression of programmed death-ligand 1 (PD-L1). After treatment with alectinib, the pathological form changed from adenocarcinoma into squamous cell carcinoma without...

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Detalhes bibliográficos
Publicado no:Pathol Oncol Res
Main Authors: Zhang, Yan, Qin, Yaping, Xu, Hongen, Yao, Qihui, Gao, Yalan, Feng, Yushu, Ren, Jingli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262189/
https://ncbi.nlm.nih.gov/pubmed/34257603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.637745
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