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Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial function and calcium signaling

The cellular and molecular mechanisms that drive neurodegeneration remain poorly defined. Recent clinical trial failures, difficult diagnosis, uncertain etiology, and lack of curative therapies prompted us to re-examine other hypotheses of neurodegenerative pathogenesis. Recent reports establish tha...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Jadiya, Pooja, Garbincius, Joanne F., Elrod, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262011/
https://ncbi.nlm.nih.gov/pubmed/34233766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01224-4
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