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Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids

BACKGROUND: The first step in SARS-CoV-2 infection is binding of the virus to angiotensin converting enzyme 2 (ACE2) on the airway epithelium. Asthma affects over 300 million people world-wide, many of whom may encounter SARS-CoV-2. Epidemiologic data suggests that asthmatics who get infected may be...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: O’Beirne, Sarah L., Salit, Jacqueline, Kaner, Robert J., Crystal, Ronald G., Strulovici-Barel, Yael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261394/
https://ncbi.nlm.nih.gov/pubmed/34233672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01782-0
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