Expression and Functional Evaluation of Recombinant Anti-receptor Activator of Nuclear Factor Kappa-B Ligand Monoclonal Antibody Produced in Nicotiana benthamiana

Denosumab, an anti-receptor activator of nuclear factor-kappa B ligand antibody (anti-RANKL), is a fully human monoclonal antibody (mAb) available for the treatment of osteoporosis. In the present study, an anti-RANKL mAb was transiently expressed using the geminiviral expression system in Nicotiana...

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Bibliographische Detailangaben
Veröffentlicht in:Front Plant Sci
Hauptverfasser: Boonyayothin, Wanuttha, Sinnung, Sirorut, Shanmugaraj, Balamurugan, Abe, Yoshito, Strasser, Richard, Pavasant, Prasit, Phoolcharoen, Waranyoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Plant Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261044/
https://ncbi.nlm.nih.gov/pubmed/34249053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2021.683417
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