Progesterone Treatment Does Not Decrease Serum Levels of Biomarkers of Glial and Neuronal Cell Injury in Moderate and Severe Traumatic Brain Injury Subjects: A Secondary Analysis of the Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment (ProTECT) III Trial

Early treatment of moderate/severe traumatic brain injury (TBI) with progesterone does not improve clinical outcomes. This is in contrast with findings from pre-clinical studies of progesterone in TBI. To understand the reasons for the negative clinical trial, we investigated whether progesterone tr...

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Pubblicato in:J Neurotrauma
Autori principali: Korley, Frederick, Pauls, Qi, Yeatts, Sharon D., Jones, Courtney Marie Cora, Corbett-Valade, Emily, Silbergleit, Robert, Frankel, Michael, Barsan, William, Cahill, Nathan D., Bazarian, Jeffrey J., Wright, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260894/
https://ncbi.nlm.nih.gov/pubmed/33319651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2020.7072
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