An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility

Ras homologous guanosine triphosphatases (RhoGTPases) control several cellular functions, including cytoskeletal actin remodeling and cell migration. Their activities are downregulated by GTPase‐activating proteins (GAPs). Although RhoGTPases are implicated in bone remodeling and osteoclast and oste...

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Detalhes bibliográficos
Publicado no:JBMR Plus
Main Authors: Mäkitie, Riikka E., Henning, Petra, Jiu, Yaming, Kämpe, Anders, Kogan, Konstantin, Costantini, Alice, Välimäki, Ville‐Valtteri, Medina‐Gomez, Carolina, Pekkinen, Minna, Salusky, Isidro B., Schalin‐Jäntti, Camilla, Haanpää, Maria K., Rivadeneira, Fernando, Bassett, John H. Duncan, Williams, Graham R., Lerner, Ulf H., Pereira, Renata C., Lappalainen, Pekka, Mäkitie, Outi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260816/
https://ncbi.nlm.nih.gov/pubmed/34258505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10509
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