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Lactate sensing mechanisms in arterial chemoreceptor cells

Classically considered a by-product of anaerobic metabolism, lactate is now viewed as a fundamental fuel for oxidative phosphorylation in mitochondria, and preferred over glucose by many tissues. Lactate is also a signaling molecule of increasing medical relevance. Lactate levels in the blood can in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Torres-Torrelo, Hortensia, Ortega-Sáenz, Patricia, Gao, Lin, López-Barneo, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260783/
https://ncbi.nlm.nih.gov/pubmed/34230483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24444-7
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