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Pharmacological modulation of RORα controls fat browning, adaptive thermogenesis, and body weight in mice
Beiging is an attractive therapeutic strategy to fight against obesity and its side metabolic complications. The loss of function of the nuclear transcription factor RORα has been related to a lean phenotype with higher thermogenesis in sg/sg mice lacking this protein. Here we show that pharmacologi...
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| Vydáno v: | Am J Physiol Endocrinol Metab |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8260366/ https://ncbi.nlm.nih.gov/pubmed/33252251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00131.2020 |
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