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Holistic characterization of single-hepatocyte transcriptome responses to high-fat diet

During nutritional overload and obesity, hepatocyte function is grossly altered, and a subset of hepatocytes begins to accumulate fat droplets, leading to nonalcoholic fatty liver disease (NAFLD). Recent single-cell studies revealed how nonparenchymal cells, such as macrophages, hepatic stellate cel...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Park, Sung Rye, Cho, Chun-Seok, Xi, Jingyue, Kang, Hyun Min, Lee, Jun Hee
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260362/
https://ncbi.nlm.nih.gov/pubmed/33103450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00391.2020
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