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Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG

The peroxisome proliferator-activated receptors (PPARs) have been previously implicated in the pathophysiology of skeletal muscle dysfunction in women with breast cancer (BC) and animal models of BC. This study investigated alterations induced in skeletal muscle by BC-derived factors in an in vitro...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Wilson, Hannah E., Stanton, David A., Rellick, Stephanie, Geldenhuys, Werner, Pistilli, Emidio E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260354/
https://ncbi.nlm.nih.gov/pubmed/33439777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00264.2020
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