Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films

Febuxostat (FXS) is a potent antigout drug with poor water solubility and relative high first-pass effect leading to moderate oral bioavailability (<49%). This study aimed to increase FXS solubility and bioavailability by optimizing sublingual fast-dissolving films (SFs) containing a selected FXS...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Habib, Basant A., Abd El-Samiae, Amina S., El-Houssieny, Boushra M., Tag, Randa
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260042/
https://ncbi.nlm.nih.gov/pubmed/34176376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1927247
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