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Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation

Chloride intracellular channels (CLICs) are a unique family of evolutionarily conserved metamorphic proteins, switching between stable conformations based on redox conditions. CLICs have been implicated in a wide variety biological processes including ion channel activity, apoptosis, membrane traffi...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Weston, Rory M., Schmitt, Rebecca E., Grotewiel, Mike, Miles, Michael F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259981/
https://ncbi.nlm.nih.gov/pubmed/34228751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246224
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